Israel Academy of Sciences and Humanities esale e le setho ho tloha ka 1952.
E ngotsoe ke molao ka 1961, Israel Academy of Sciences and Humanities e na le bo-ramahlale le litsebi tse hlahelletseng tsa Iseraele tse mashome a supileng, bao, ka thuso ea basebetsi le likomiti tsa Academy, ba sebeletsang e le setsi sa naha sa borutehi ba Isiraele. Mesebetsi ea Academy e kenyelletsa ho boloka le ho phahamisa bokhabane ba bohlale ba Iseraele, ho eletsa 'muso ka litaba tse amanang le saense, ho tšehetsa lichelete le ho phatlalatsa lipatlisiso tsa boleng ba nako e telele, le ho boloka likamano tse matla le balekane ba thuto le mekhatlo ea saense linaheng tse ling.
Sekolo se thehile Israel National Science Foundation, hammoho le lichelete tse ling tse ngata tse tšehelitsoeng ke bafani ba poraefete. E boloka dikamano tse haufi le diofisi tsa matona ditabeng tse amanang le leano la naha la saense le thuto e phahameng Iseraeleng mme e bile le seabo ho theheng mokgatlo o hokahanyang wa ditheo tsa mmuso le tseo e seng tsa mmuso tse amehang saenseng. E emela Isiraele mekhatlong ea mahlale ea machabeng, ho kenyeletsoa hoo e batlang e le litho tsohle tsa mahlale tsa ICSU, 'me e na le litumellano tsa tšebelisano-'moho ea mahlale le likolo tse fetang mashome a mararo tsa kantle ho naha le mekhatlo ea litsebi.
Sebaka sa Iseraele, mateanong a litsela tsa Europe, Asia le Afrika, se thehile boemo bo ikhethang boo ho bona Iseraele e leng setho sa mekhatlo e fapaneng ea libaka. Israel e boloka boemo ba Observer ho European Science Foundation le Botho bo Kopanetsoeng ho Mananeo a Moralo oa mahlale a European Union. Sekolo sena ke setho se thehiloeng sa ALLEA (All European Academies) le AASA (Mokhatlo oa Likolo tsa Saense tsa Asia) le Lekhotla la Baokameli ba Makhotla a Saense le Lithuto tsa Middle East (Jordan, Bolaoli ba Palestina, Egepeta, Iseraele le US). Mopresidente oa Akademi o boetse o sebetsa Lekhotleng la InterAcademy le Phanele ea InterAcademy.
