IUPHAR esale e le setho ho tloha ka 1972.
IUPHAR e thehiloe ka 1959 e le karolo ea International Union of Physiological Sciences (IUPS) mme ea fetoha mokhatlo o ikemetseng ka 1965.
IUPHAR ke mokhatlo oa boithaopo, o sa etseng phaello oa mekhatlo ea naha e emelang litsebi tsa meriana tsa linaha tseo e leng litho le mekhatlo ea libaka. Litho tsa hona joale li kenyelletsa mekhatlo ea naha ea 55 ea litsebi tsa meriana, mekhatlo ea libaka tsa phekolo ea meriana likarolong tse sa tšoaneng tsa lefats'e le mekhatlo e mengata ea saense e nang le lipakane tse amanang le tsa IUPHAR. IUPHAR e boetse e amohela litho tsa setho le tsa khoebo. IUPHAR e emela likarolo tsohle tsa pharmacology ka kutloisiso ea eona e pharaletseng, ho tloha ho theory ho ea ho pharmacology ea bongaka, lefats'eng ka bophara.
IUPHAR ke setho sa ISC, mme e nka karolo mosebetsing oa likomiti tsa eona tsa mahlale. Union e fumana kananelo ea machaba, haholo-holo ke Mokhatlo oa Machaba a Kopaneng oa Thuto le Saense (UNESCO) ’me ke mokhatlo oo e seng oa ’muso o likamanong tsa molao le Mokhatlo oa Lefatše oa Bophelo (WHO).
Lipheo tsa mantlha tsa IUPHAR ke:
E le ho finyella lipakane tsena, IUPHAR e tšehetsa letoto la likopano tsa machaba, e hlophisa maeto bakeng sa baprofesa ba etileng, e theha mananeo a khethehileng a ho ruta, 'me e khothalletsa pharmacology ka har'a mekhatlo e khethiloeng ea machaba le ea naha. Sebaka sa Marang-rang sa IUPHAR se kenyelletsa lithuso tsa thuto ea pharmacology ka lipuo tse ngata le likhokahano tsa kharikhulamo ea pharmacology lefatšeng ka bophara.
Komiti ea IUPHAR e mabapi le Receptor Nomenclature and Drug Classification (NC-IUPHAR) e phatlalalitse letoto la li-volumes, tse kenyeletsang The IUPHAR Compendium of Receptor Characterization and Classification and The IUPHAR Compendium of Voltage-gated Ion Channels.